Atomoxetine Hydrochloride – Impurity C (CAS No. 1643684-06-3): Essential Reference Standard for Pharmaceutical Analysis

Atomoxetine Hydrochloride – Impurity C (CAS No. 1643684-06-3): 

Atomoxetine Hydrochloride – Impurity C, also known as p-Methyl Atomoxetine Hydrochloride, is a highly specialized pharmaceutical reference standard. Supplied by Pharmaffiliates Pvt. Ltd. under Catalogue No. PA 28 35030, it plays a vital role in drug quality control, regulatory compliance, and advanced analytical testing.

Chemical and Physical Information

  • CAS Number: 1643684-06-3

  • Molecular Formula: C₁₇H₂₂ClNO

  • Molecular Weight: 291.82

  • Synonyms: (3R)-N-Methyl-3-(4-methylphenoxy)-3-phenylpropan-1-amine Hydrochloride, N-Methyl-γ-(4-methylphenoxy)benzenepropanamine Hydrochloride, N-Methyl-3-phenyl-3-(p-tolyloxy)propan-1-amine Hydrochloride, Atomoxetine Related Compound C.

Storage and Handling Guidelines

To maintain its stability and integrity, Atomoxetine Hydrochloride – Impurity C should be stored in tightly sealed containers at refrigerated temperatures between 2–8 °C. As it is hygroscopic, proper handling is essential to prevent moisture absorption. The product is shipped under ambient conditions to ensure safe and convenient transportation.

Applications in Pharmaceutical Development

This impurity standard is indispensable in various stages of drug research and manufacturing:

  • Impurity Profiling: Identifying and quantifying related substances to ensure product safety.

  • Analytical Method Validation: Verifying the accuracy, precision, and reproducibility of testing methods.

  • Quality Control Testing: Meeting strict international pharmaceutical quality standards.

  • Stability Studies: Monitoring product behavior over time under different environmental conditions.

By using well-characterized impurity standards like this, pharmaceutical companies enhance the reliability of their analytical results, meet regulatory requirements efficiently, and streamline approval processes.

Pharmaffiliates’ Expertise Beyond Reference Standards

Pharmaffiliates is not just a supplier—it is a full-service end-to-end CRDMO provider in India for both small and large molecules. The company delivers:

  • Biologic Early Development Services in India – including advanced analytics for biologics and monoclonal antibody analytics.

  • Custom Synthesis – of pharmaceutical impurities, APIs, chiral molecules, stable isotopes, and metabolites.

  • Regulatory Documentation Support – with CMC data preparation, stability reports, and compliance filings.

  • Concept-to-Commercial CDMO Partnership in India – supporting the complete drug development lifecycle.

  • Spray Dried Dispersions CRDMO Expertise – for enhanced drug solubility and bioavailability.

Final Note

In modern pharmaceutical science, the role of impurity standards like Atomoxetine Hydrochloride – Impurity C cannot be overstated. From ensuring batch-to-batch consistency to meeting global regulatory expectations, it is a small but powerful component in the journey from drug discovery to market availability.


Comments

Post a Comment

Popular posts from this blog

D-Leu7-Triptorelin (CAS 321709-37-9) | Peptide Impurity Standard by Pharmaffiliates

Image
D-Leu7-Triptorelin (CAS 321709-37-9) | Peptide Impurity Standard by Pharmaffiliates D-Leu7-Triptorelin, identified by CAS number 321709-37-9 , is a synthetic peptide categorized as an in-house impurity and research-grade reference material. It is structurally related to the well-known GnRH analogue Triptorelin , a peptide used in hormonal and oncology research. Unlike the parent compound, D-Leu7-Triptorelin is primarily intended for laboratory, analytical, and reference purposes rather than therapeutic use. Chemical Profile and Specifications Chemical Name: Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-D-leucyl-L-arginyl-L-prolyl Molecular Formula: C₆₄H₈₂N₁₈O₁₃ Molecular Weight: 1311.47 g/mol Product Code: PA PEP 003537 Category: Peptides / Reference Standards Storage Condition: 2-8 °C (Refrigerator) Shipping Condition: Ambient These precise attributes help researchers and analytical laboratories maintain consistency in peptide test...
Read more

CAS 2857963-60-9: Premium Peptide Reference Standard for Advanced Research & QC

Image
CAS 2857963-60-9: Premium Peptide Reference Standard for Advanced Research & QC CAS 2857963-60-9, also known as 3,6,9,12,15,18,21,24,27,30-Decamethyl-4,7,10,13,16,19,22,25,28,31-decaoxo-3,6,9,12,15,18,21,24,27,30-decaazadotriacontanoic acid , represents a highly specialized peptide-based reference compound widely utilized in pharmaceutical research, analytical testing, and peptide formulation development. Due to its extended chain length and multiple carbonyl-amide functional groups, this molecule plays a key role in validating purification protocols, analyzing peptide impurities, and studying long-chain peptide analogs. This compound is especially valuable in R&D facilities, peptide synthesis laboratories, CROs, CDMOs, and regulated pharmaceutical environments , where accuracy, traceability, and certified quality standards are critical. Chemical Profile & Structure CAS Number 2857963-60-9 Chemical Nature Long-chain poly-peptide analog Functional Groups Carbonyl, amide...
Read more

Exploring D-Leu-4-OB3 (CAS 289056-32-2): A Key Research Peptide with Scientific Potential

Image
Exploring D-Leu-4-OB3 (CAS 289056-32-2): A Key Research Peptide with Scientific Potential Pharmaffiliates Private Limited lists D-Leu-4-OB3 under catalogue number PA PEP 003427 , with the CAS number 289056-32-2 . This compound falls under the “Peptides” category on the Pharmaffiliates website and is offered primarily for research purposes . The chemical name of the compound is: L-Threonine, L-seryl-L-cysteinyl-L-seryl-D-leucyl-L-prolyl-L-glutaminyl-; L-seryl-L-cysteinyl-L-seryl-D-leucyl-L-prolyl-L-glutaminyl-L-threonine; Mus musculus [D-Leu-4]-OB3 peptide; Mouse [D-Leu-4]-OB3. Its molecular formula is C₂₉H₅₀N₈O₁₂S , with a molecular weight of 734.82 g/mol . The product page specifies storage conditions of 2-8 °C with ambient shipping . These details ensure that researchers are aware of both the storage and handling requirements of the compound. Composition and Structure D-Leu-4-OB3 is a synthetic research peptide that contains both L- and D-amino acids . The “D-Leu” part of t...
Read more