Isomenthol | CAS 23283-97-8

 

Chemical Identity

(+)-Isomenthol (CAS 23283-97-8) is a chiral monoterpene alcohol widely used in pharmaceuticals, flavor and fragrance industries, and analytical chemistry.

  • IUPAC Name: (1R,3S,4R)-4-Menthan-3-ol

  • Molecular Formula: C₁₀H₂₀O

  • Molecular Weight: 156.27 g/mol

  • Appearance: Off-white solid

  • Melting Point: Approximately 79–80°C

  • Storage Conditions: Store at 2–8°C in a dry, dark place

Chemical Properties

(+)-Isomenthol is a stereoisomer of menthol, featuring a hydroxyl group (-OH) attached to a cyclohexane ring. It is often used as a reagent in chemical synthesis and as a reference compound in analytical studies.

Industrial Applications

1. Pharmaceutical Industry
In pharmaceuticals, (+)-Isomenthol is valued for its cooling and soothing properties. It is incorporated into topical formulations to provide a refreshing sensation and alleviate discomfort associated with skin conditions.

2. Flavor and Fragrance Industry
It is employed for its minty aroma and cooling effect, enhancing the sensory experience in perfumes, cosmetics, and non-flavor applications.

3. Analytical Chemistry
(+)-Isomenthol serves as an analytical standard and is used in quantitative titration and other analytical techniques.

Synonyms

  • Levomenthol - Impurity D (EP/BP)

  • (1S-(1a,2b,5b))-5-Methyl-2-(1-methylethyl)cyclohexanol

  • (1R,3S,4R)-(+)-Menthol

  • (+)-Isomenthol

  • (1S,2R,5R)-(+)-Isomenthol

  • D-Isomenthol

Safety and Handling

Handle (+)-Isomenthol with standard laboratory safety precautions. Use appropriate personal protective equipment (gloves, goggles), work in a well-ventilated area, and follow safety guidelines for chemicals.

Availability

(+)-Isomenthol is commercially available in various quantities and purities to meet the needs of research, pharmaceutical, and industrial applications.   


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